NORENA Arnaud
2017 Research grant
Project status: active
Origin of tinnitus and hyperacusis: new mechanistic explorations.
The aim of the research project is to study the contribution of a mechanism at the origin of hyperacusis and tinnitus that has until now received little attention, and which is involved in the inhibition of transmission via the nerves.
To answer this question, Dr Norena will use multidisciplinary approaches such as molecular biology to evaluate the inhibition mechanisms, electrophysiology to measure nerve activity and pharmacology to study how this mechanism is regulated.
This research work will make it possible to identify a promising new targeted therapy to treat these very disabling symptoms.
2016 Early Career Scientific Prize
Project status: closed
During his university studies, Arnaud Norena gravitated toward biology and in particular neuroscience, which he considers an interface between mind and matter. At the end of his Master of Research, he applied to different laboratories to carry out his thesis and was intrigued by one of the suggested topics on tinnitus, seeing the potential of this field.
Prof. Norena has chosen a career in research since he sees the profession as offering freedom. He has always wanted to explore and invent.
Currently a team leader at the Sensory and Cognitive Neuroscience Laboratory in Marseille[M1], he works with numerous hearing health professionals, such as ENT doctors and hearing care practitioners, and would like to use this prize for new explorations. Developing acoustic therapies to overcome tinnitus would be a fine reward.
Doctor Arnaud Norena
Investigator-Team leader
Sensory and Cognitive Neuroscience Laboratory (Laboratoire de Neurosciences Sensorielles et Cognitives), Aix-Marseille University, Marseille, France
Related scientific publication(s):
- Vinay Parameshwarappa, Laurent Pezard, Arnaud Jean Norena. Changes in the spatiotemporal pattern of spontaneous activity across a cortical column after noise trauma. J Neurophysiol. 2021 Dec 22. doi: 10.1152/jn.00262.2021. Online ahead of print.
- Philippe Fournier, Dany Paleressompoulle, Marie-José Esteve Fraysse, Fabien Paolino, Arnaud Devèze, Frédéric Venail, Arnaud Noreña. Exploring the middle ear function in patients with a cluster of symptoms including tinnitus, hyperacusis, ear fullness and/or pain. Hear Res. 2022 May 13;422:108519. doi: 10.1016/j.heares.2022.108519. Online ahead of print.