EL-AMRAOUI Aziz

Project status: active

Directed by Dr. Aziz El-Amraoui, the “Progressive sensory deficits, pathophysiology and therapy” team conducts research projects aimed at better understanding the origin and mechanisms leading to hearing and sight loss (late and/or progressive) with a view to developing suitable treatment.

In addition to introducing therapeutic approaches (corrective and/or protective) to prevent, slow down, stop or correct deterioration in sight and/or hearing, this team also aims to understand how external factors such as noise, light or age influence the onset, progression and severity of sensory impairment.

Doctor Aziz El-Amraoui
Investigator-Team leader
Institut de l’Audition, Paris, France

Related scientific publication(s):

• Catherine Botto, Deniz Dalkara, Aziz El-Amraoui. Progress in Gene Editing Tools and Their Potential for Correcting Mutations Underlying Hearing and Vision Loss. Front Genome Ed. 2021 Oct 28;3:737632. doi: 10.3389/fgeed.2021.737632. eCollection 2021. 
• Sedigheh Delmaghani, Aziz El-Amraoui. The genetic and phenotypic landscapes of Usher syndrome: from disease mechanisms to a new classification. Hum Genet. 2022 Apr;141(3-4):709-735 .doi: 10.1007/s00439-022-02448-7. Epub 2022 Mar 30.