Sous-titre
ZINE Azel
Contenu
Body
Project status: closed
In most cases, hearing loss is associated with the destruction of the hair cells in the inner ear.
This can be due to environmental factors (exposure to noise, ototoxic drugs, aging, etc.) or genetic factors. In humans and other mammals, the body is incapable of regenerating hair cells. The resulting hearing loss is often irreversible.
Ms. Hanae Lahlou is a doctoral student. Her research project is supervised by Prof. Azel Zine and aims to develop innovative therapies for generating new hair cells from stem cells.
Professor Azel Zine
Investigator
Supervisor of Hanae Lalhou's doctoral thesis
Sensory and Cognitive Neuroscience Laboratory, Aix-Marseille Université, Marseille, France
Related scientific publication(s):
- Hanae Lahlou, Alejandra Lopez-Juarez, Arnaud Fontbonne, Emmanuel Nivet , Azel Zine. Modeling human early otic sensory cell development with induced pluripotent stem cells. PLoS One. 2018 Jun 14;13(6):e0198954. doi: 10.1371/journal.pone.0198954. eCollection 2018.
- Hanae Lahlou, Emmanuel Nivet, Alejandra Lopez-Juarez, Arnaud Fontbonne, Said Assou, Azel Zine. Enriched Differentiation of Human Otic Sensory Progenitor Cells Derived From Induced Pluripotent Stem Cells. Front Mol Neurosci. 2018 Dec 20;11:452. doi: 10.3389/fnmol.2018.00452. eCollection 2018.
- Alejandra Lopez-Juarez, Hanae Lahlou, Chantal Ripoll, Yves Cazals, Jean Michel Brezun, Quan Wang, Albert Edge, Azel Zine. Engraftment of Human Stem Cell-Derived Otic Progenitors in the Damaged Cochlea. Mol Ther. 2019 Jun 5;27(6):1101-1113. doi: 10.1016/j.ymthe.2019.03.018. Epub 2019 Apr 2.