BATHELLIER Brice
2019 Institut de l'Audition
Project status: active
Brice Bathellier’s “Dynamic of the auditory system and multisensory perception” team is studying the computational principles for processing auditory and multisensory information.
To do so, they are combining advanced analysis and modeling techniques with a broad range of experimental approaches, including two-photon calcium imaging, multichannel electrophysiology, optogenetics and behavioral analysis of auditory perception. The team's main projects include the large-scale deciphering of sound representations in the mouse auditory system, the development of optogenetic methods to generate auditory perceptions through targeted activation of the central neuronal networks, and the exploration of the perceptual role of neuronal connections between the brain areas processing different sensory modes.
The Hearlight project aims to develop and test an innovative cortical implant to rehabilitate hearing disorders, by light stimulation of the main sound processing center in the brain.
2016 Research grant
Project status: closed
A laureate of the call for laboratory projects in 2016, Brice Bathellier, a researcher in the CNRS Neuroscience, Information and Complexity Unit (UNIC) in Gif-sur-Yvette, France, is studying and attempting to elucidate with innovative imaging techniques the calculations enabling the brain to encode sound and generate auditory perception.
This work will improve the definition of auditory information processing used in hearing aids.
Doctor Brice Bathellier
Investigator - Team leader
CNRS Neuroscience, Information and Complexity Unit (UNIC),
Gif-sur-Yvette, France
Institut de l'Audition, Paris, France
Related scientific publication(s):
- Kuchibhotla K, Bathellier B. Neural encoding of sensory and behavioral complexity in the auditory cortex. Curr Opin Neurobiol. 2018 Oct;52:65-71. doi: 10.1016/j.conb.2018.04.002.Curr Opin Neurobiol. 2018 Oct.
- Ceballo S, Piwkowska Z, Bourg J, Daret A, Bathellier B. Targeted Cortical Manipulation of Auditory Perception. Neuron 2019 Dec 18;104(6):1168-1179.e5. doi: 10.1016/j.neuron.2019.09.043. Epub 2019 Nov 11.
- Ceballo S, Bourg J, Kempf A, Piwkowska Z, Daret A, Pinson P, Deneux T, Rumpel S, Bathellier B. Cortical recruitment determines learning dynamics and strategy. Nat Commun. 2019 Apr 1;10(1):1479. doi: 10.1038/s41467-019-09450-0.Epub 2019 Nov 11.
- Deneux T, Harrell ER, Kempf A, Ceballo S, Filipchuk A, Bathellier B. Context-dependent signaling of coincident auditory and visual events in primary visual cortex. Elife. 2019 May 23;8:e44006. doi: 10.7554/eLife.44006.
- Evan R Harrell, Anthony Renard, Brice Bathellier. Fast cortical dynamics encode tactile grating orientation during active touch. Sci Adv. 2021 Sep 3;7(36):eabf7096. doi: 10.1126/sciadv.abf7096. Epub 2021 Sep 3.
- Anthony Renard, Evan R Harrell, Brice Bathellier. Olfactory modulation of barrel cortex activity during active whisking and passive whisker stimulation. Nat Commun. 2022 Jul 2;13(1):3830. doi: 10.1038/s41467-022-31565-0.
- Sebastian Ceballo, Thomas Deneux, Mariana Siliceo, Brice Bathellier. Differential roles of auditory and visual cortex for sensory detection in mice. C R Biol. 2022 May 11;345(1):75-89. doi: 10.5802/crbiol.72.
- Anton Filipchuk, Joanna Schwenkgrub, Alain Destexhe, Brice Bathellier. Awake perception is associated with dedicated neuronal assemblies in cerebral cortex. Nat Neurosci. 2022 Sep 28. doi: 10.1038/s41593-022-01168-5. Online ahead of print.